Mac OS X / nginx / MariaDB / PHP / Aegir (MEMPÆ)
At Realityloop we've found Ægir to be a major time saver and great tool for deplying Drupal websites, so several months ago we started on the path to get Aegir running locally on our Mac's for development purposes, with one caveat.. using NGINX instead of Apache!
Without further ado here is how to do it both by Video and Text instructions, please follow the instructions carefully as this process has been refined to make the process as painless as possible. Yes, this works on both Lion and Snow Leopard.
Provided by: Brian Gilbert